Research is uncovering upsides of taking it for a variety of conditions, and we’ll likely see more to come, but it’s also on us to recognize that this is an unfolding story and proceed with caution. ![]() With so much fanfare, it’s easy to ignore the fact that CBD is a potent compound that's far from exhaustively understood. The most adverse side effect of consuming grapefruit while taking statins is rhabdomyolysis, a breakdown of muscle tissue that can be dangerous for kidneys and cause kidney failure or even death, but it is extremely rare, according to a study published in January 2016 in the American Journal of Medicine so rare that not eating grapefruit wouldn't reduce the risk by much. The market for CBD products is predicted to pass $22 billion over the next four years, and that's coming with the expected hurricane of fact-obscuring hype. And it’s important to check with your doctor before taking CBD, especially if you’re taking other medications. But since the compound appears to exert similar effects as grapefruit, caution is needed.Īt a minimum, the evidence at this point suggests that grapefruit warnings on medications should also apply to CBD. Thus, for statins like simvastatin and lovastatin, with a relatively short half-life, taking grapefruit juice just in the evening produces about half the effect. One of the big problems with CBD at the moment is we don’t really know yet which drugs are affected the most, and it’s difficult to identify exact levels of risk because the research has a lot of catching up to do after decades of science-blocking illegality. Drugs with a narrow “therapeutic window” (they must stay within a certain blood-concentration range) are especially susceptible. Other statins, such as pravastatin, do not interact with. When statin takers eat large amounts of grapefruit, the level. ![]() When statin takers eat large amounts of grapefruit, the level of statins in their blood can increase, raising the possibility of side effects. This is only a problem with simvastatin, atorvastatin and lovastatin. Grapefruit contains a chemical that can interfere with your body’s ability to break down or metabolize certain statin medications. Grapefruit contains a chemical that can interfere with your bodys ability to break down or metabolize certain statin medications. A chemical in grapefruit can increase the level of statin in the bloodstream, which can make side-effects from the statin more likely. Per the Lipitor package insert, one study showed that drinking one glass of grapefruit juice (8 ounces) with atorvastatin resulted in an increased drug concentration of 37. Past research has warned that eating grapefruit or drinking grapefruit juice and taking statins for high cholesterol may increase your risk for complications such as rhabdomyolysis, the breakdown of muscle tissue that may lead to kidney damage, joint pain, and muscle pain. ![]() A high dose of a med could become a dangerously high dose, or even an overdose. Do not eat grapefruit or drink grapefruit juice if you are taking some statins. The enzymes that both grapefruit and CBD inhibit are thought to break down a significant percentage of prescription and over-the-counter medications, so the potential for problems could be high.Ī low dose of a med could become a high dose if it’s not properly broken down and eliminated.
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